The Fists of Fate are widely regarded as a universal Unique in Diablo 4 Season 10, but some builds make better use of them than others. Knowing which setups maximize their potential helps players decide whether to prioritize farming for this item.
High-attack builds are the natural match for the Fists of Fate. Rogues using Dance of Knives or Rapid Fire rely on hitting multiple times in quick succession, greatly increasing the odds of landing maximum-damage rolls. Spiritborn unique item diablo 4 projectile builds offer similar synergy, as each projectile counts as an independent attack.
Sorcerers also find strong value in the Fists of Fate, particularly with Chain Lightning and Ice Shard setups. These builds already generate high attack frequency and benefit from additional critical strike chances provided by the Unique’s affixes.
Barbarians focusing on Whirlwind or Frenzy also perform well with this item. Each spin or strike rolls the dice multiple times, raising the likelihood of achieving a devastating burst during encounters with dense groups of enemies.
Druids, especially those emphasizing shapeshifting attacks, can take advantage of the gloves’ random spike potential. Werewolf and Werebear builds that maintain constant strikes are well-suited to the damage variance.
The classes least suited for the Fists of Fate are those relying on damage-over-time mechanics. Shadowblight Necromancers, for example, see less impact since the majority of their damage ticks are unaffected by the Unique’s affix. For them, equipment that boosts DoT directly is a better investment.
Still, the broad compatibility of the Fists of Fate makes them one of the few Uniques that can find a home in nearly any build. The Diablo 4 gold randomness of their damage is offset by their consistently strong affixes, meaning even classes that aren’t fully optimized for them still gain solid value.
In conclusion, while nearly every build can benefit from the Fists of Fate, the most explosive results come from high-frequency attackers. Players focusing on speed and constant damage output will find this Chaos Unique indispensable in Season 10.